Categories
Prevention of diabetes

The Link Between Your Immune System and Diabetes

Additional Tips for Managing Type 2 Diabetes

Additional Tips for Managing Type 2 Diabetes

In addition to regular medical appointments, individuals with type 2 diabetes can take several steps to manage their condition effectively:

  • Monitor blood sugar levels regularly and keep a record of results
  • Follow a healthy meal plan that includes a variety of fruits, vegetables, whole grains, and lean proteins
  • Incorporate physical activity into your daily routine, aiming for at least 30 minutes of exercise most days of the week
  • Take medications as prescribed by your healthcare provider
  • Maintain a healthy weight to reduce the risk of complications

By following these recommendations and working closely with healthcare professionals, individuals with type 2 diabetes can better control their condition and reduce the likelihood of serious complications.

Risks of Elevated Blood Sugar Levels

Risks of Elevated Blood Sugar Levels

Although rare in type 2 diabetes, high blood sugar levels can lead to life-threatening conditions like hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) due to infection and dehydration, underscoring the importance of managing insulin levels.

Both HHS and DKA pose significant risks to health.

Recognizing Urgent Symptoms

Recognizing Urgent Symptoms

If experiencing frequent urination, excessive thirst, nausea, confusion, drowsiness, or shortness of breath, seek immediate medical attention as these symptoms could signal HHS or DKA, requiring prompt intervention to avoid severe outcomes.

Do not attempt to drive yourself to the hospital; instead, contact emergency services or ask someone for assistance.

Next Review Date

This article was last reviewed on February 10, 2025, with the next review scheduled for February 10, 2028.

The immune system serves as a shield against harmful pathogens, with lymphocytes identifying and combating bacteria and viruses to safeguard the body.

Immunity strengthens over time, enhancing the body’s ability to recognize and fight off infections effectively. Vaccines play a pivotal role in educating the immune system, preventing severe illnesses.

The lack of correlation between system-level factors and patient outcomes shifted the focus to patient-level determinants in a conceptual model. Variations in outcomes and care processes were observed among different patient subgroups. Younger patients were less likely to receive recommended care processes and control risk factors effectively. Differences in sex were noted in the use of aspirin and lipid-lowering medications, as well as in risk factor control.
Household income and education did not strongly influence care processes but were connected to intermediate outcomes and mortality. Neighborhood socioeconomic status also played a role in disparities in health outcomes. Health-related behaviors, such as smoking and physical activity, were key predictors of effective control.
Health-related behaviors had a modest impact on outcomes but did not account for sociodemographic differences. Smoking prevalence varied based on age, education, gender, and ethnicity. Regular physical activity levels differed depending on age, gender, race, and education. Rates of self-monitoring of blood glucose varied among ethnic groups, with income affecting medication usage.
Depression was more common and significantly linked to poor risk factor control in African American patients when compared to white patients. Addressing mental health issues is crucial for improving outcomes in individuals with diabetes.
The majority of participants in the TRIAD study were obese at the onset, with a higher prevalence among women and African Americans. Obesity was associated with reduced regular walking and control over cardio-metabolic risk factors, particularly among African Americans.
Physicians tended to treat patients of different racial and ethnic backgrounds differently in terms of hypertension, lipid management, and blood pressure control. Non-white groups were less likely to receive treatment for poorly controlled A1C levels.
Patient evaluations of providers’ skills did not correlate with risk factor control or educational disparities in health behaviors. Trust in physicians, however, was linked to better control of cardiovascular disease risk factors.
Spanish-speaking patients in the TRIAD study were more likely to have bilingual physicians and receive specific diabetes care services. A1C levels were somewhat higher in Spanish-speaking Latinos compared to English-speaking Latinos.
The management intensity in 2000 did not have an impact on racial/ethnic disparities in risk factor control or health behaviors.
Integrated health systems with intensive disease management showed improvements in diabetes care processes but did not affect intermediate outcomes. Future interventions should target processes that directly influence outcomes.
Cost-shifting strategies in healthcare might reduce preventive services and medication usage, especially for lower-income individuals. Eliminating copayments for diabetes medications could be beneficial.
The TRIAD study identified numerous patient-level factors linked to self-care and intermediate outcomes, suggesting the need for tailored interventions for different diabetic subpopulations.

  • 24. Karter AJ, Stevens MR, Herman WH, Ettner S, Marrero DG, Safford MM, Engelgau MM, Curb JD, Brown AF. Group dedicated to Translating Research Into Action for Diabetes. Impact of personal expenses on diabetes prevention services: findings from the Translating Research Into Action for Diabetes Study. Published in Diabetes Care in 2003;26:2294–2299 [PubMed] [Google Scholar]
  • 25. Tseng CW, Tierney EF, Gerzoff RB, Dudley RA, Waitzfelder B, Ackermann RT, Karter AJ, Piette J, Crosson JC, Ngo-Metzger Q, Chung R, Mangione CM. Investigating racial/ethnic and economic disparities in medication underuse due to costs among insured diabetic individuals: Insights from The TRIAD Study. Published in Diabetes Care in 2008;31:261–266 [PubMed] [Google Scholar]
  • 26. Selby JV, Swain BE, Gerzoff RB, Karter AJ, Waitzfelder BE, Brown AF, Ackermann RT, Duru OK, Ferrara A, Herman W, Marrero DG, Caputo D, Narayan KM. Collaborative effort of the TRIAD Study Group. Addressing the gap between effective diabetes care processes and poor outcomes: Lessons from Translating Research Into Action for Diabetes. Published in Medical Care in 2007;45:1144–1153 [PubMed] [Google Scholar]
  • 27. Schmittdiel JA, Ettner SL, Fung V, Huang J, Turk N, Quiter ES, Swain BE, Hsu JT, Mangione CM. Impact of Medicare Part D coverage gap on diabetic beneficiaries. Published in the American Journal of Managed Care in 2009;15:189–193 [PubMed] [Google Scholar]
  • 28. Fung V, Mangione CM, Huang J, Turk N, Quiter E, Schmittdiel JA, Hsu J. Navigating the coverage gap: Assessing Part D drug costs and adherence among Medicare Advantage Prescription Drug Plan recipients with diabetes. Published in Health Services Research in December 2009 [Epub ahead of print] [PubMed] [Google Scholar]
  • 29. Duru OK, Mangione CM, Hsu J, Steers WN, Quiter E, Turk N, Ettner SL, Schmittdiel JA, Tseng C-W. Coping with medication expenses among diabetic Medicare Part D patients: insights from the Translating Research into Action for Diabetes Study. Article accepted for publication in the Journal of the American Geriatrics Society [PubMed] [Google Scholar]
  • 30. Schmittdiel JA, Uratsu CS, Karter AJ, Heisler M, Subramanian U, Mangione CM, Selby JV. Exploring reasons behind failure of diabetes patients to meet recommended risk factor targets: Examining adherence versus treatment intensification. Published in the Journal of General Internal Medicine in 2008;23:588–594 [PubMed] [Google Scholar]
  • 31. Schmittdiel JA, Uratsu CS, Fireman BH, Selby JV. Evaluating the efficiency of diabetes care management within managed care systems. Published in the American Journal of Managed Care in 2009;15:295–301 [Google Scholar]
  • 32. Subramanian U, Ackermann RT, Brizendine EJ, Saha C, Rosenman MB, Willis DR, Marrero DG. Influence of advanced access scheduling on diabetes care processes and intermediate outcomes, focusing on utilization. Published in the Journal of General Internal Medicine in 2009;24:327–333 [PubMed] [Google Scholar]
  • 33. Duru OK, Schmittdiel JA, Dyer W, Parker M, Uratsu C, Chan J, Karter AJ. Impact of utilizing mail-order pharmacies on adherence to diabetes-related medications. Published in the American Journal of Managed Care in 2010;16:33–40 [PubMed] [Google Scholar]
  • 34. McEwen LN, Hsiao VC, Nota-Kirby B, Kulpa G, Schmidt KG, Herman WH. Assessment of a managed care disease management program on diabetes healthcare. Published in the American Journal of Managed Care in 2009;15:575–580 [PubMed] [Google Scholar]
  • 35. Kerr EA, Krein SL, Vijan S, Hofer TP, Hayward RA. Strategies to avoid errors in chronic disease quality measurement: a perspective on the future of technical quality measures. Published in the American Journal of Managed Care in 2001;7:1033–1043 [Google Scholar]
  • 36. Kerr EA, Smith DM, Hogan MM, Hofer TP, Krein SL, Bermann M, Hayward RA. Developing improved quality metrics: highlighting cases where patients labeled as receiving “poor quality” care are actually receiving good care. Published in Medical Care in 2003;41:1173–1182 [PubMed] [Google Scholar]
  • 37. Selby JV, Uratsu CS, Fireman B, Schmittdiel JA, Peng T, Rodondi N, Karter AJ, Kerr EA. Enhancing treatment intensity and risk factor management: moving towards more clinically relevant quality indicators. Published in Medical Care in 2009;47:395–402 [PubMed] [Google Scholar]
  • 38. Duru OK, Gerzoff RB, Selby JV, Brown AF, Ackermann RT, Karter AJ, Ross S, Steers N, Herman WH, Waitzfelder B, Mangione CM. Identifying factors contributing to racial disparities in diabetes outcomes: Insights from the Translating Research in Action for Diabetes Study. Published in Medical Care in 2009;47:700–706 [PubMed] [Google Scholar]
  • 39. Gregg EW, Karter AJ, Gerzoff RB, Safford M, Brown A, Tseng C-W, Waitzfelder B, Herman W, Mangione C, Selby J, Thompson T, Dudley RA. Characteristics of insured individuals with persistent gaps in diabetes services: findings from the Translating Research into Action for Diabetes Study. Published in Medical Care in 2010;48:31–37 [PubMed] [Google Scholar]
  • 40. Subramanian U, Schmittdiel JA, Gavin N, Traylor A, Uratsu CS, Selby JV, Mangione CM. Investigating how patient age influences treatment and control of cardiovascular disease risk factors in individuals with diabetes. Published in the Journal of General Internal Medicine in 2009;24:1049–1052 [PubMed] [Google Scholar]
  • Articles from Diabetes Care courtesy of the American Diabetes Association:
    – Gender disparities in healthcare quality regarding prevention of ischemic heart disease in diabetic patients
    – Gender differences in control and management of modifiable cardiovascular disease risk factors in diabetic patients
    – Assessing the impact of physician and patient gender, as well as gender concordance, on control and treatment of cardiovascular disease risk factors in diabetes
    – Relationship between race, ethnicity, socioeconomic status, and quality of care for diabetic adults in managed care settings
    – Influence of health behaviors and quality of care on Latinos with diabetes in managed care settings
    – Addressing neighborhood issues, health behaviors, and diabetes outcomes among diabetic adults in managed care
    – Exploring educational gaps in smoking rates among diabetic adults
    – Educational differences in health behaviors among diabetic patients
    – Predictors for consistent walking habits in diabetic individuals in managed care
    – Analyzing time invested in healthcare: do socioeconomically disadvantaged patients spend more or less time on diabetes self-care?
    – Evaluation of a brief depression severity assessment
    – Impact of patient race/ethnicity and patient-physician race/ethnicity concordance on management of cardiovascular disease risk factors for diabetic patients
    – Preventive counseling among women with a history of gestational diabetes
    – Connecting clinical care strategies with reduction of racial/ethnic disparities in diabetes care
    – Interventions to enhance diabetes management in primary care, outpatient, and community settings
    – Enhancing chronic disease management at community health centers
    – Unintended consequences of limitations on Medicare drug benefits
    – Controlled trial on value-based insurance design
    – Long-term outcomes of intensive glucose control in type 2 diabetes
    – The paradox of inequality: examining public health approaches and vulnerable populations